A core aspect of the Enerverse is the connections, possibilities, threats, and opportunities created by having the ability to access the multiverse. The primary mechanism for accessing the multiverse is a homebrew city called Usley that has been retconned on the western shore of the Dragonmere in Faerun. Through this connection to the multiverse, players and GMs will be able to connect and experience different worlds, and also different game systems for those worlds. The ruleset used for the multiverse connection is Labyrinth from Kobold Press.
These are unique gameplay formats, mini-settings, or special scenarios you can experience in the Enerverse.
If we stick with 5e, there are still dozens of available campaign settings that we can play in beyond the official WotC-developed Faerun. Here is a partial list of what is currently available.